sEMTor – The EMT simulator
An interactive, agent-based model to simulate epithelial-to-mesenchymal transitions-like events in a pseudostratified epithelium.

Developed by Steffen Plunder, see the companion articles.


Go to online simulations:

EMT in tall pseudostratified epithelium.
Keywords: neuroepithelium, chick embryo, neural crest delamination
Reference: "Modelling variability and heterogeneity of EMT scenarios highlights nuclear positioning and protrusions as main drivers of extrusion"
Steffen Plunder, Cathy Danesin, Bruno Glise, Marina A Ferreira, Sara Merino Aceituno and Eric Theveneau, Nature Communications (2024).
EMT in short pseudostratified epithelium.
Keywords: neuroepithelium, chick embryo, neural crest delamination
"Non-apical mitoses contribute to cell delamination during mouse gastrulation"

Evangéline Despin-Guitard, Viviane S. Rosa, Steffen Plunder, Navrita Mathiah, Kristof Van Schoor, Eliana Nehme, Sara Merino-Aceituno, Joaquim Egea, Marta N. Shahbazi, Eric Theveneau & Isabelle Migeotte, Nature Communications (2024).

Source code: