An
interactive, agent-based model to simulate epithelial-to-mesenchymal transitions-like events in a
pseudostratified epithelium.
Developed by Steffen Plunder, see the companion articles.
Go to online simulations:
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EMT in tall pseudostratified epithelium.
Keywords: neuroepithelium, chick embryo, neural crest delamination
Reference: "Modelling variability and heterogeneity of EMT scenarios highlights nuclear positioning and protrusions as
main drivers of extrusion"
Steffen Plunder, Cathy Danesin, Bruno Glise, Marina A Ferreira, Sara Merino Aceituno and Eric Theveneau,
2023, bioRxiv.
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EMT in short pseudostratified epithelium.
Evangéline Despin-Guitard, Steffen Plunder, Navrita Mathiah, Eric Theveneau and Isabelle Migeotte, 2024, bioRxiv.
Keywords: neuroepithelium, chick embryo, neural crest delamination
"Occurrence of non-apical mitoses at the primitive streak, induced by relaxation of actomyosin and acceleration of the cell cycle, contributes to cell delamination during mouse gastrulation"
Evangéline Despin-Guitard, Steffen Plunder, Navrita Mathiah, Eric Theveneau and Isabelle Migeotte, 2024, bioRxiv.
